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Assistant Researcher Yi-Fan Chen,

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Yi-Fan Chen (陳儀帆)

Assistant Researcher
PhD, Cornell University
 
Fields of Interest
Biological Physics, Soft Condensed Matter/Biological Liquid Crystals, Application of Synchrotron-based X-ray Scattering and Crystallography Techniques, Application of High-Pressure Physics
 
Research Statement
We are interested in applying the synchrotron- and neutron-based scattering and diffraction techniques, as well as high-pressure methods to studying the structures, dynamics and phase transitions of lyotropic liquid crystals and of biological soft matter. We aim to explore how the function of matter is correlated with its structure and dynamics. This knowledge will not only advance our understanding towards the matter but also facilitate fabricating materials with desirable properties. Currently, our research interests include:
  1. Mechanisms of the Phase Behavior Exhibited by Electrically Charged Phospholipids and Other Lyotropic Liquid Crystals
  2. Correlations Between the Mechanical and Dynamical Properties of Lipid Membranes
  3. Development of the High-Pressure Cryocooling Technique for Protein Crystals and of Other Scientific Instruments
  4. Structual and Dynamical Studies of the Interactions Between Water and Biological Soft Matter
  5. Application of Neutron-based Scattering Techniques to Studies of Biology and Materials Systems
We welcom graduate and undergraduate students who enjoy conducting experimental science and instrumentation. We also seek potential collaborators who are interested in structurally and dynamically characterizing their biology and materials systems.
 
Publications (Selected): 
  1. Chen, Y. -F.; Tate, M. W.; Gruner, S. M. 2012. “Phase Behavior of Dioleoylcardiolipin-Water Dispersions.” In preparation.
  2. Chen, Y. -F.; Tate, M. W.; Gruner, S. M. 2009. “Facilitating protein crystal cryoprotection in thick-walled plastic capillaries by high-pressure cryocooling.” Journal of Applied Crystallography, Volume 42, p525-530.
  3. Y. -F. Chen, S. M. Gruner and E. Snell. “A universal additive for high pressure cryocooling”, Protein Structure Initiative Bottleneck Workshop, Bethesda, MD, April 14-16 (2008)
  4. Kim, C. U.; Chen, Y. -F.; Tate, M. W.; Gruner, S. M. 2008. “Pressure-induced high-density amorphous ice in protein crystals.” Journal of Applied Crystallography, Volume 41, p1-7.
  5. Y. -F. Chen, C. U. Kim and S. M. Gruner. “Automated high-pressure cryoprotection and noble gas phasing for high-throughput protein structure determination”, Protein Structure Initiative Bottleneck Workshop, Bethesda, MD, March 19-20 (2007)
  6. Dai, C. -A.; Chen, Y. -F.; Liu, M. -W. 2006. "Thermal properties measurements of renatured gelatin using conventional and temperature modulated differential scanning calorimetry." Journal of Applied Polymer Science, Volume 99, p1795-1801.
Email:
 
Phone:
(03) 5715131 ext.34304
 
Office:
510
 
Address:
NationalTsingHuaUniversity
Department of Engineering and System Science
Sec. 2, Kuang-Fu Road, Hsinchu, 30013, Taiwan
 
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