2015/05/06 歡迎 台大機械系 范士岡 副教授 蒞臨演講,講題:Constructing Heterogeneous Microcomponents on an Electro-Microfluidic Platform

2015/05/06 歡迎 台大機械系 范士岡 副教授 蒞臨演講,講題:Constructing Heterogeneous Microcomponents on an Electro-Microfluidic Platform

本週邀請到 台大機械系 范士岡 副教授 進行專題演講
講題:Constructing Heterogeneous Microcomponents on an Electro-Microfluidic Platform
時間:2015/05/06 15:30~17:20
地點:NE69演講廳

Synthesis and assembly of multi-functional, heterogeneous, and encoded microcomponents, or building blocks, are essential to engineering hierarchical, complex, and three-dimensional structures. The elaborately organized architectures devise metamaterials that hold new physical properties unusual in nature or artificial tissues that reappear physiological functions by imitating natural and biological arrangements. Here we demonstrate synthesis and assembly of microcomponents by electrowetting-on-dielectric (EWOD) and dielectrophoresis (DEP) on a robotic electro-microfluidic platform. The platform is capable of (1) driving different droplets of hydrogel prepolymers before cross-linking, (2) arranging particles or cells in the droplets, and (3) forming microcomponents by cross-linking droplets in different shapes. In the presentation, we will demonstrate the synthesis and assembly of different hydrogel microcomponents containing different dyes and particles. The heterogeneous structures with cell adhesive GelMA (gelatin methacrylate) and non-adhesive PEG-DA (Poly(ethylene glycol) diacrylate) surfaces are prepared for cell culture. The culture of fibroblasts NIH/3T3, neonatal mouse cardiomyocyte, and endothelia HUVEC on the engineered structures synthesized and assembled on the robotic electro-microfluidic platform will be reported.